- The two principal herbs in this blend are horse chestnut and cayenne pepper, each of which has been used historically, and supported scientifically, in supporting hemorrhoids or piles. Horse chestnut helps reduce blood vessel permeability and can be useful for both varicose veins and hemorrhoids or piles. Studies done in Europe found that horse chestnut helped to increase blood flow, strengthen connective tissue, tighten up veins, and decrease redness and swelling. Cayenne pepper can be useful
